SCHEMBL16627924

SCHEMBL16627924

CC(C)(C)c1cc(/N=C/c2ccccc2O)cc(C(C)(C)C)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIRT2 Q8IXJ6 2/20 0.61
TSHR P16473 1/20 0.55
CA12 O43570 3/20 0.51
CA2 P00918 3/20 0.51
CA9 Q16790 2/20 0.51
CA1 P00915 1/20 0.48
MAPT P10636 5/20 0.46
KDM4E B2RXH2 3/20 0.46
GAA P10253 3/20 0.46
ALDH1A1 P00352 2/20 0.46
ALOX15 P16050 2/20 0.46
USP2 O75604 1/20 0.46
ALOX12 P18054 1/20 0.46
HTT P42858 1/20 0.46
HSD17B10 Q99714 1/20 0.46
SMN1; SMN2 Q16637 2/20 0.45
MAOB P27338 4/20 0.45
KMT2A Q03164 3/20 0.43
PKM P14618 2/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12416829 0.78 CA12 (0.53) SIRT2TSHRCA12CA2CA9
SCHEMBL2494083 0.77 SIRT2 (1.00) SIRT2TSHRCA12CA2CA9
SCHEMBL2494084 0.77 SIRT2 (1.00) SIRT2TSHRCA12CA2CA9
SCHEMBL23644527 0.76 MAPT (0.64) SIRT2TSHRCA2CA1MAPT
SCHEMBL18489461 0.76 MAPT (0.64) SIRT2TSHRCA2CA1MAPT
SCHEMBL2937662 0.75 SIRT2 (0.74) SIRT2TSHRCA12CA2CA9
SCHEMBL2492350 0.75 SIRT2 (0.74) SIRT2TSHRCA12CA2CA9
SCHEMBL2492349 0.75 SIRT2 (0.74) SIRT2TSHRCA12CA2CA9
2-((Phenylimino)Methyl)Phenol SCHEMBL347862 0.75 SIRT2 (0.88) SIRT2TSHRCA12CA2CA9
2-((Phenylimino)Methyl)Phenol SCHEMBL29424118 0.75 SIRT2 (0.88) SIRT2TSHRCA12CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
WO-2015050583-A1 METAL CONTAINING CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2015-04-09 WO disclosed