Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 5/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21600440 | 0.83 | ALDH1A1 (0.45) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL1067996 | 0.77 | ERN1 (0.52) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL30417210 | 0.77 | ERN1 (0.52) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL18534818 | 0.73 | CYP3A4 (0.39) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL8264926 | 0.68 | ERN1 (0.63) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL70194 | 0.67 | HSD17B10 (0.72) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL29375263 | 0.67 | HSD17B10 (1.00) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL591469 | 0.67 | HSD17B10 (1.00) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL28568064 | 0.66 | ALDH1A1 (0.50) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 | |
| SCHEMBL6395364 | 0.64 | ALDH1A1 (0.45) | TSHRHSD17B10ALDH1A1HPGDCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469799-B2 | Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2016-10-18 | — | — | US | disclosed |
| US-20150337190-A1 | Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts | DOW SILICONES CORPORATION | 2015-11-26 | — | — | US | disclosed |
| US-9139699-B2 | Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts | DOW CORNING CORPORATION (US) | 2015-09-22 | — | — | US | disclosed |
| WO-2015050583-A1 | METAL CONTAINING CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS | DOW CORNING CORPORATION (US) | 2015-04-09 | — | — | WO | disclosed |