SCHEMBL70194

SCHEMBL70194

Oc1cc(Cl)cc(Cl)c1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 8/20 0.72
TSHR P16473 6/20 0.72
ALDH1A1 P00352 5/20 0.72
CYP3A4 P08684 4/20 0.72
RECQL P46063 2/20 0.72
HPGD P15428 4/20 0.62
TTR P02766 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
THRB P10828 2/20 0.54
MAPK1 P28482 2/20 0.54
ALOX15 P16050 2/20 0.54
ALOX12 P18054 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
HIF1A Q16665 2/20 0.54
NR1I2 O75469 2/20 0.54
LMNA P02545 2/20 0.54
PGR P06401 2/20 0.54
ADORA3 P0DMS8 2/20 0.54
MAPT P10636 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL29265637 0.90 HSD17B10 (0.59) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL184648 0.84 HSD17B10 (1.00) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL6355918 0.84 TSHR (0.56) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL8872103 0.84 HSD17B10 (1.00) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL11291920 0.81 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL20380030 0.81 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL29827111 0.81 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL2808115 0.81 HSD17B10 (0.93) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL4214817 0.78 HSD17B10 (0.65) HSD17B10TSHRALDH1A1CYP3A4RECQL
SCHEMBL8071292 0.77 ALDH1A1 (0.72) HSD17B10TSHRALDH1A1CYP3A4RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 160 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118702085-A Method for regulating specific surface area of carbon material 三明学院 2024-09-27 CN claimed
CN-117402494-A Complex high-strength polyarylene sulfide based composite material and preparation and application thereof 新凝合科技(成都)有限公司 2024-01-16 CN claimed
CN-115838453-A High-molecular heteronuclear porphyrin complex and preparation method and application thereof 中国科学院长春应用化学研究所 2023-03-24 CN claimed
CN-115779962-A Bi-component organic catalytic system consisting of hydrogen bond donor-nucleophilic bifunctional reagent and organic boron reagent and application thereof 浙江大学 2023-03-14 CN claimed
CN-115746034-A Three-function organic catalyst, preparation method and application thereof 浙江大学 2023-03-07 CN claimed
CN-111944148-B High-optical-property degradable polycarbonate and preparation method thereof 大连理工大学 2022-05-17 CN claimed
CN-113307973-B Poly disulfide material with excellent optical performance and preparation method thereof 大连理工大学 2022-04-12 CN claimed
CN-112812230-B Catalytic load polymer and preparation method and application thereof 浙江大学 2022-03-25 CN claimed
CN-112851924-B Recyclable nitrogen-containing polycarbonate plastic synthesis method 大连理工大学 2022-02-15 CN claimed
CN-113461926-A Chemical synthesis method of poly beta-hydroxy fatty acid ester 大连理工大学 2021-10-01 CN claimed
US-8435810-B2 Method of manufacturing organic light emitting display device SAMSUNG DISPLAY CO., LTD. (KR) 2013-05-07 US claimed
US-20120018679-A1 DISPLAY DEVICE, METHOD OF MANUFACTURING THE SAME, AND COMPOSITION FOR USE IN MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-01-26 US claimed
US-20110207254-A1 Method of manufacturing organic light emitting display device SAMSUNG DISPLAY CO., LTD. (KR) 2011-08-25 US claimed
US-20100300472-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND L'OREAL S.A. (FR) 2010-12-02 US claimed
US-7838186-B2 Photoconductors containing charge transport chelating components XEROX CORPORATION (US) 2010-11-23 US claimed
US-7462433-B2 Undercoat layer containing charge transfer molecule, andTiO2; imaging layer; charge transfer molecule complexes with the TiO2 to form coordination bonds and the coordination bonds provide a reduction in ghosting; electrophotographic imaging members; improved image quality XEROX CORPORATION (US) 2008-12-09 US claimed
US-20080286670-A1 Photoconductors containing charge transport chelating components XEROX CORPORATION 2008-11-20 US claimed
US-20070153371-A1 DISPLAY DEVICE, METHOD OF MANUFACTURING THE SAME, AND COMPOSITION FOR USE IN MANUFACTURING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2007-07-05 US claimed
US-20070048639-A1 Undercoat layer containing charge transfer molecule, andTiO2; imaging layer; charge transfer molecule complexes with the TiO2 to form coordination bonds and the coordination bonds provide a reduction in ghosting; electrophotographic imaging members; improved image quality XEROX CORPORATION (US) 2007-03-01 US claimed
US-4487975-A Etherification of phenols RHONE-POULENC INDUSTRIES (FR) 1984-12-11 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100300472-A1 METHOD FOR STRAIGHTENING KERATINOUS FIBERS USING HEATING MEANS AND AN AROMATIC COMPOUND KRT18, TUBB4A, TUBB4B HSD17B10 501/4885TSHR 4707/4885ALDH1A1 1099/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.