SCHEMBL16627993

SCHEMBL16627993

Oc1ccccc1-c1ncccc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.47
PDE5A O76074 1/20 0.47
ALDH1A1 P00352 4/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 2/20 0.47
PTPRC P08575 2/20 0.47
CTSL P07711 1/20 0.47
CTSS P25774 1/20 0.47
PTPN13 Q12923 1/20 0.47
KMT2A Q03164 2/20 0.46
TDP2 O95551 1/20 0.46
NSD2 O96028 1/20 0.46
ABL1 P00519 1/20 0.46
PLCG1 P19174 1/20 0.46
CES1 P23141 1/20 0.46
PAX8 Q06710 1/20 0.46
RIN1 Q13671 1/20 0.46
MEN1 O00255 1/20 0.46
THRB P10828 1/20 0.46
BLM P54132 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3434698 0.89 PTPRC (0.50) RIPK1PDE5AALDH1A1KDM4EHPGD
SCHEMBL29693684 0.89 PTPRC (0.50) RIPK1PDE5AALDH1A1KDM4EHPGD
SCHEMBL30777260 0.87 PTPRC (0.48) RIPK1PDE5AALDH1A1KDM4EHPGD
SCHEMBL29038944 0.87 RIPK1 (0.49) RIPK1PDE5AALDH1A1KDM4EHPGD
SCHEMBL4083689 0.86 ALDH1A1 (0.52) RIPK1PDE5AALDH1A1KDM4EHPGD
SCHEMBL28480001 0.84 KDM4E (0.50) RIPK1PDE5AKDM4EPTPRCCTSL
SCHEMBL27741522 0.84 MAPT (0.47) RIPK1PDE5AALDH1A1KDM4EHPGD
SCHEMBL27768716 0.84 CDC25B (0.43) RIPK1PDE5AALDH1A1KDM4EHPGD
SCHEMBL15317422 0.84 KDM4E (0.54) ALDH1A1KDM4EHPGDPTPRCCTSL
SCHEMBL687180 0.83 KDM4E (0.55) ALDH1A1KDM4EHPGDKMT2ATDP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-9469799-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2016-10-18 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-20150337190-A1 Metal Containing Condensation Reaction Catalysts, Methods for Preparing the Catalysts, and Compositions Containing the Catalysts DOW SILICONES CORPORATION 2015-11-26 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
US-9139699-B2 Metal containing condensation reaction catalysts, methods for preparing the catalysts, and compositions containing the catalysts DOW CORNING CORPORATION (US) 2015-09-22 US disclosed
WO-2015050583-A1 METAL CONTAINING CONDENSATION REACTION CATALYSTS, METHODS FOR PREPARING THE CATALYSTS, AND COMPOSITIONS CONTAINING THE CATALYSTS DOW CORNING CORPORATION (US) 2015-04-09 WO disclosed