SCHEMBL15317422

SCHEMBL15317422

Oc1cccnc1-c1ccccc1F

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 9/20 0.54
NPC1 O15118 1/20 0.42
ALDH1A1 P00352 2/20 0.42
HPGD P15428 1/20 0.42
MPI P34949 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GABRG2 P18507 1/20 0.41
GABRB3 P28472 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRA3 P34903 1/20 0.41
PTPRC P08575 2/20 0.41
CTSL P07711 1/20 0.41
CTSS P25774 1/20 0.41
PTPN13 Q12923 1/20 0.41
KMT2A Q03164 2/20 0.41
PDK2 Q15119 1/20 0.41
TDP2 O95551 1/20 0.41
NSD2 O96028 1/20 0.41
ABL1 P00519 1/20 0.41
PLCG1 P19174 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28480001 0.85 KDM4E (0.50) KDM4ENPC1MPIL3MBTL1GABRG2
SCHEMBL16627993 0.84 RIPK1 (0.47) KDM4EALDH1A1HPGDL3MBTL1PTPRC
SCHEMBL27586448 0.78 ALDH1A1 (0.47) KDM4EALDH1A1HPGDL3MBTL1PTPRC
SCHEMBL30022581 0.77 PTGS1 (0.49) KDM4ENPC1ALDH1A1L3MBTL1GABRG2
SCHEMBL687180 0.76 KDM4E (0.55) KDM4ENPC1ALDH1A1HPGDMPI
SCHEMBL29769309 0.76 KDM4E (0.55) KDM4ENPC1ALDH1A1HPGDMPI
SCHEMBL28338125 0.76 KDM4E (0.46) KDM4ENPC1ALDH1A1HPGDL3MBTL1
SCHEMBL3791925 0.76 KDM4E (0.41) KDM4ENPC1GABRG2GABRB3GABRA5
SCHEMBL29071480 0.76 KDM4E (0.46) KDM4ENPC1ALDH1A1HPGDL3MBTL1
SCHEMBL6579855 0.75 KDM4E (0.65) KDM4ENPC1ALDH1A1L3MBTL1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3318566-B1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2020-06-24 EP disclosed
US-20190248804-A1 SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES IDEMITSU KOSAN CO., LTD. (JP) 2019-08-15 US disclosed
US-20190131547-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC IRELAND LTD (IE) 2019-05-02 US disclosed
US-10249827-B2 Azadibenzofurans for electronic applications UDC IRELAND LIMITED (IE) 2019-04-02 US disclosed
US-9978952-B2 Fused heterocyclic aromatic derivative, organic electroluminescence element material, and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-22 US disclosed
US-9978952-B2 Fused heterocyclic aromatic derivative, organic electroluminescence element material, and organic electroluminescence element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-05-22 US disclosed
EP-3318566-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS UDC Ireland Limited (IE) 2018-05-09 EP disclosed
US-9923151-B2 Material for organic electroluminescent elements, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-20 US disclosed
US-9923151-B2 Material for organic electroluminescent elements, and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2018-03-20 US disclosed
EP-3063153-B1 AZADIBENZOTHIOPHENES FOR ELECTRONIC APPLICATIONS IDEMITSU KOSAN CO (JP) 2018-03-07 EP disclosed
US-20140183486-A1 NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2014-07-03 US disclosed
US-20140183486-A1 NOVEL COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENCE DEVICE, AND ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD (JP) 2014-07-03 US disclosed
US-20140175419-A1 FUSED HETEROCYCLIC AROMATIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-06-26 US disclosed
US-20140175419-A1 FUSED HETEROCYCLIC AROMATIC DERIVATIVE, ORGANIC ELECTROLUMINESCENCE ELEMENT MATERIAL, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. 2014-06-26 US disclosed
WO-2014044722-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS BASF SE (DE) 2014-03-27 WO disclosed
EP-2660890-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME Idemitsu Kosan Co., Ltd. (JP) 2013-11-06 EP disclosed
US-20130270540-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-10-17 US disclosed
US-20130270540-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2013-10-17 US disclosed
CN-101208328-B Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals SANOFI AVENTIS 2012-02-29 CN disclosed
CN-101208328-A Heteroaryl-substituted amides comprising a saturated linker group, and their use as pharmaceuticals SANOFI AVENTIS (FR) 2008-06-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190248804-A1 SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES CDY1; CDY1B, CDYL, CBX8 KDM4E 212/4885NPC1 3800/4885ALDH1A1 1323/4885
US-20190131547-A1 AZADIBENZOFURANS FOR ELECTRONIC APPLICATIONS AZI2, BRPF1, CCNB1 KDM4E 1361/4885NPC1 4635/4885ALDH1A1 547/4885
US-10249827-B2 Azadibenzofurans for electronic applications AZI2, BRPF1, CCNB1 KDM4E 1361/4885NPC1 4635/4885ALDH1A1 547/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.