Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28624771 | 0.85 | — | — | |
| SCHEMBL15273567 | 0.79 | HTR2C (0.35) | CTSDCTSLCTSBCTSS | |
| SCHEMBL15274043 | 0.77 | SSTR4 (0.32) | — | |
| SCHEMBL16629290 | 0.76 | — | — | |
| SCHEMBL16629272 | 0.72 | MAPK14 (0.36) | CTSBCTSS | |
| SCHEMBL15273728 | 0.72 | HSD11B1 (0.32) | — | |
| SCHEMBL15885408 | 0.70 | BRD4 (0.36) | — | |
| SCHEMBL28624773 | 0.70 | NCEH1 (0.38) | — | |
| SCHEMBL16629274 | 0.69 | BRD4 (0.34) | CTSDCTSLCTSBCTSS | |
| SCHEMBL15261301 | 0.69 | HTR2C (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113292496-B | Synthetic method of Laratinib intermediate | 安徽联创生物医药股份有限公司 | 2023-03-10 | — | — | CN | claimed |
| CN-113292496-A | Synthetic method of Laolatinib intermediate | 安徽联创生物医药股份有限公司 | 2021-08-24 | — | — | CN | claimed |
| CN-113292496-B | Synthetic method of Laratinib intermediate | 安徽联创生物医药股份有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-113292496-B | Synthetic method of Laratinib intermediate | 安徽联创生物医药股份有限公司 | 2023-03-10 | — | — | CN | disclosed |
| CN-113292496-A | Synthetic method of Laolatinib intermediate | 安徽联创生物医药股份有限公司 | 2021-08-24 | — | — | CN | disclosed |
| CN-113292496-A | Synthetic method of Laolatinib intermediate | 安徽联创生物医药股份有限公司 | 2021-08-24 | — | — | CN | disclosed |
| WO-2015050989-A2 | MACROCYCLIC COMPOUNDS FOR THE TREATMENT OF PROLIFERATIVE DISEASES | CS THERAPEUTICS INC. (US) | 2015-04-09 | — | — | WO | disclosed |