SCHEMBL1662997

SCHEMBL1662997

COc1ccc(C=O)cc1C=O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.70
TSHR P16473 2/20 0.70
AOX1 Q06278 1/20 0.63
FDPS P14324 1/20 0.59
TDP1 Q9NUW8 2/20 0.58
HPGD P15428 2/20 0.58
TRIM24 O15164 1/20 0.58
ALDH5A1 P51649 1/20 0.58
ABAT P80404 1/20 0.58
TRIM33 Q9UPN9 1/20 0.58
KDM4E B2RXH2 2/20 0.57
TTR P02766 1/20 0.54
ALDH1A3 P47895 1/20 0.49
CYP2A6 P11509 1/20 0.48
MAPT P10636 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
LMNA P02545 2/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
TUBB1 Q9H4B7 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8068922 0.86 ALDH1A1 (0.53) ALDH1A1TSHRAOX1FDPSTDP1
SCHEMBL26908574 0.85 ALDH1A1 (0.53) ALDH1A1TSHRAOX1FDPSTDP1
SCHEMBL4146840 0.85 MAPT (0.57) ALDH1A1TSHRAOX1TDP1HPGD
3,4-Dimethoxybenzaldehyde SCHEMBL5803811 0.84 ALDH1A1 (0.71) ALDH1A1TSHRAOX1FDPSTDP1
SCHEMBL13521550 0.84 FDPS (0.87) ALDH1A1TSHRFDPSTDP1HPGD
SCHEMBL2892484 0.83 ALDH1A1 (0.70) ALDH1A1TSHRAOX1FDPSTDP1
SCHEMBL30600410 0.83 ALDH1A1 (0.70) ALDH1A1TSHRAOX1FDPSTDP1
SCHEMBL26908597 0.83 ALDH1A1 (0.50) ALDH1A1TSHRAOX1FDPSTDP1
3,4-Dimethoxybenzaldehyde SCHEMBL5308959 0.83 ALDH1A1 (1.00) ALDH1A1TSHRAOX1FDPSTDP1
3,4-Dimethoxybenzaldehyde SCHEMBL1330962 0.83 ALDH1A1 (1.00) ALDH1A1TSHRAOX1FDPSTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1386603-A1 Use of diamines having at least one quaternised group and dialdehydes for dyeing keratin fibres L'OREAL (FR) 2004-02-04 EP claimed
EP-3947344-B1 2,2'-(1,3-PHENYLENEDIMETHYLIDYNE)-BIS-HYDRAZINECARBOXIMIDAMIDE DERIVATIVES AS RETROMER STABILIZERS FOR THE TREATMENT OF NEUROLOGICAL DISEASES OSPEDALE SAN RAFFAELE SRL (IT) 2025-10-01 EP disclosed
US-20240166867-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2024-05-23 US disclosed
EP-4286448-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2023-12-06 EP disclosed
CN-114341103-B Aminoguanhydrazones as retrograde transport stabilizers useful in the treatment of neurological diseases 圣拉斐尔医院有限公司 2023-11-10 CN disclosed
CN-116940559-A Cyclic diol compound, process for producing the compound, and use of the compound 新日本理化株式会社 2023-10-24 CN disclosed
CN-116829618-A Thermoplastic resin and optical lens comprising the same 三菱瓦斯化学株式会社 2023-09-29 CN disclosed
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
WO-2022163684-A1 CYCLIC DIOL COMPOUND, METHOD FOR PRODUCING SAID COMPOUND, AND USE OF SAID COMPOUND 新日本理化株式会社 2022-08-04 WO disclosed
WO-2022163674-A1 THERMOPLASTIC RESIN AND OPTICAL LENS INCLUDING SAME 三菱瓦斯化学株式会社 2022-08-04 WO disclosed
US-20150252043-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2015-09-10 US disclosed
US-20140243324-A1 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS LIGAND PHARMACEUTICALS INCORPORATED (US) 2014-08-28 US disclosed
EP-2642994-A2 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS Ligand Pharmaceuticals Incorporated (US) 2013-10-02 EP disclosed
US-20120295904-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES LIGAND PHARMACEUTICALS INC. (US) 2012-11-22 US disclosed
EP-2488486-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES Ligand Pharmaceuticals Inc. (US) 2012-08-22 EP disclosed
WO-2012068406-A2 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS LIGAND PHARMACEUTICALS INCORPORATED (US) 2012-05-24 WO disclosed
WO-2011046954-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES LIGAND PHARMACEUTICALS INC. (US) 2011-04-21 WO disclosed
WO-2010054908-A1 PRODUCTION OF SOLAR CELL MODULES EVONIK RÖHM GMBH (DE) 2010-05-20 WO disclosed
WO-2010054907-A1 MOLDING COMPOUNDS FOR THE PRODUCTION OF SOLAR CELL MODULES EVONIK RÖHM GMBH (DE) 2010-05-20 WO disclosed
EP-1386603-A1 Use of diamines having at least one quaternised group and dialdehydes for dyeing keratin fibres L'OREAL (FR) 2004-02-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140243324-A1 USE OF HEMATOPOIETIC GROWTH FACTOR MIMETICS HGF, EPOR, MPL ALDH1A1 3228/4885TSHR 1674/4885AOX1 3562/4885
US-20150252043-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES MPL, CSF3R, HGF ALDH1A1 2736/4885TSHR 1185/4885AOX1 4192/4885
US-20120295904-A1 HEMATOPOIETIC GROWTH FACTOR MIMETIC SMALL MOLECULE COMPOUNDS AND THEIR USES MPL, CSF3R, HGF ALDH1A1 2736/4885TSHR 1185/4885AOX1 4192/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.