Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 10/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 2/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16630787 | 0.84 | KDM4C (0.40) | MAPK1ALDH1A1PIK3C3GRM5IRAK4 | |
| SCHEMBL16620394 | 0.83 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL19223210 | 0.81 | MAPK1 (0.54) | MAPK1 | |
| SCHEMBL17567308 | 0.77 | L3MBTL1 (0.41) | MAPK1ALDH1A1PDE4DPDE10A | |
| SCHEMBL16620566 | 0.74 | MAPK1 (0.35) | MAPK1 | |
| SCHEMBL15294473 | 0.71 | HPGD (0.42) | MAPK1ALDH1A1NAMPTPDE4DPDE10A | |
| SCHEMBL15248449 | 0.71 | ALDH1A1 (0.46) | MAPK1ALDH1A1NAMPTPDE4DPDE10A | |
| SCHEMBL15248177 | 0.70 | MAPK1 (0.43) | MAPK1NAMPT | |
| SCHEMBL18022537 | 0.70 | PIK3C3 (0.36) | MAPK1PIK3C3TLR8TLR7IRAK4 | |
| SCHEMBL17567307 | 0.70 | L3MBTL1 (0.41) | MAPK1ALDH1A1PDE4DPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051341-A1 | INHIBITORS OF ERK AND METHODS OF USE | ARAXES PHARMA LLC (US) | 2015-04-09 | — | — | WO | disclosed |