SCHEMBL16631199

SCHEMBL16631199

c1ccc(-c2ccc(-c3ccc(N(c4ccccc4)c4ccc(C5(c6cccc7c6oc6ccccc67)c6ccccc6-c6ccccc65)cc4)cc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 3/20 0.40
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.33
LMNA P02545 1/20 0.33
OPRK1 P41145 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GGPS1 O95749 1/20 0.33
CSF1R P07333 1/20 0.31
PDGFRB P09619 1/20 0.31
KIT P10721 1/20 0.31
FLT3 P36888 1/20 0.31
HDAC6 Q9UBN7 1/20 0.31
PTGES2 Q9H7Z7 1/20 0.31
PRKDC P78527 1/20 0.31
PLA2G2A P14555 1/20 0.30
PLA2G4A P47712 1/20 0.30
CYP2C19 P33261 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16838908 0.99 ALOX5 (0.40) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL16631106 0.95 ALOX5 (0.38) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL23939984 0.94 ALOX5 (0.39) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL18118724 0.94 ALOX5 (0.38) ALOX5GGPS1PTGES2PRKDC
SCHEMBL18118787 0.94 ALOX5 (0.38) ALOX5GGPS1PTGES2PRKDCPLA2G2A
SCHEMBL16631096 0.93 ALOX5 (0.39) ALOX5GGPS1PTGES2PRKDCPLA2G2A
SCHEMBL18118783 0.92 ALOX5 (0.39) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL16631201 0.92 ALOX5 (0.36) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL18118768 0.92 ALOX5 (0.39) ALOX5MEN1KMT2AMAPTKDM4E
SCHEMBL18118693 0.92 ALOX5 (0.39) ALOX5MEN1KMT2AMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917907-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-02-27 US disclosed
US-11917907-B2 Organic electroluminescent device ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2024-02-27 US disclosed
US-20220102633-A1 ORGANIC ELECTROLUMINESCENT DEVICE DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2022-03-31 US disclosed
US-20170213968-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-27 US disclosed
US-20170213968-A1 ORGANIC ELECTROLUMINESCENT DEVICE ROHM & HAAS ELECT MATERIALS KOREA LTD (KR) 2017-07-27 US disclosed
WO-2015050391-A1 AN ORGANIC ELECTROLUMINESCENT COMPOUND AND AN ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2015-04-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220102633-A1 ORGANIC ELECTROLUMINESCENT DEVICE SOD1, TRPC6, L1CAM ALOX5 1234/4885MEN1 3745/4885KMT2A 2928/4885
US-11917907-B2 Organic electroluminescent device SOD1, TRPC6, L1CAM ALOX5 1234/4885MEN1 3745/4885KMT2A 2928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.