Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 20/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18080223 | 0.85 | PYGL (0.39) | DGAT1 | |
| SCHEMBL16631883 | 0.85 | PYGL (0.39) | DGAT1 | |
| SCHEMBL16631860 | 0.81 | TSHR (0.33) | — | |
| SCHEMBL16631258 | 0.77 | TSHR (0.33) | — | |
| SCHEMBL18080246 | 0.76 | P2RY2 (0.51) | — | |
| SCHEMBL18081810 | 0.74 | DGAT1 (0.42) | DGAT1 | |
| SCHEMBL18080247 | 0.72 | PYGL (0.39) | — | |
| SCHEMBL16631880 | 0.72 | PYGL (0.39) | — | |
| SCHEMBL16631336 | 0.70 | PYGL (0.41) | — | |
| SCHEMBL18080221 | 0.70 | PYGL (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |