Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYGM | P11217 | 3/20 | 0.39 |
| ▸ | TK2 | O00142 | 2/20 | 0.36 |
| ▸ | SLC5A2 | P31639 | 2/20 | 0.35 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.35 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.34 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.34 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.34 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631292 | 0.87 | SLC5A2 (0.38) | PYGMTK2SLC5A2P2RY2 | |
| SCHEMBL16631314 | 0.85 | PYGM (0.37) | PYGMSLC5A2 | |
| SCHEMBL18080122 | 0.83 | P2RY2 (0.47) | P2RY2 | |
| SCHEMBL16631458 | 0.82 | TK1 (0.46) | TK2SLC5A2LGALS3 | |
| SCHEMBL16631457 | 0.82 | TK2 (0.44) | TK2LGALS1LGALS3 | |
| SCHEMBL16631273 | 0.80 | PYGM (0.39) | PYGMTK2P2RY2SLC28A1SLC28A2 | |
| SCHEMBL16554966 | 0.78 | PYGM (0.42) | PYGMTK2SLC5A2P2RY2SLC28A1 | |
| SCHEMBL15798565 | 0.78 | PYGM (0.42) | PYGMTK2SLC5A2P2RY2SLC28A1 | |
| SCHEMBL29420252 | 0.78 | PYGM (0.42) | PYGMTK2SLC5A2P2RY2SLC28A1 | |
| SCHEMBL15798458 | 0.78 | PYGM (0.42) | PYGMTK2SLC5A2P2RY2SLC28A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | PYGM 303/4885TK2 123/4885SLC5A2 3235/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.