Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 14/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | PTGES | O14684 | 2/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3859050 | 0.81 | CA12 (0.47) | CA12CA1CA2CA9FFAR1 | |
| SCHEMBL3456401 | 0.78 | ACACB (0.46) | FFAR1PTGESFFAR4 | |
| SCHEMBL16631499 | 0.77 | CA12 (0.50) | CA12CA1CA2CA9FFAR1 | |
| SCHEMBL233927 | 0.77 | CA12 (0.48) | CA12CA1CA2CA9FFAR1 | |
| SCHEMBL65650 | 0.77 | TAAR1 (0.57) | — | |
| SCHEMBL13680790 | 0.76 | FFAR1 (0.45) | FFAR1 | |
| SCHEMBL27941338 | 0.76 | CA12 (0.46) | CA12CA1CA2CA9FFAR1 | |
| SCHEMBL2556190 | 0.76 | GLA (0.47) | FFAR1KCNH2FFAR4MEN1KMT2A | |
| SCHEMBL29013833 | 0.75 | TAAR1 (0.55) | — | |
| SCHEMBL29807940 | 0.75 | TAAR1 (0.55) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051045-A2 | 3'END CAPS FOR RNAi AGENTS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |