Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.41 |
| ▸ | BCL2 | P10415 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 2/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 1/20 | 0.38 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25496062 | 0.89 | FFAR1 (0.42) | FFAR1PTPN5BCL2GPR84MPO | |
| SCHEMBL418611 | 0.86 | GPR52 (0.50) | FFAR1BCL2GPR52GPR84ACMSD | |
| SCHEMBL8413593 | 0.83 | TAAR1 (0.44) | BCL2GPR52GPR84HTR7ACMSD | |
| SCHEMBL13680784 | 0.83 | ABL1 (0.50) | FFAR1GPR52ANO1 | |
| SCHEMBL13680788 | 0.81 | MAPT (0.50) | BCL2GPR52LIPGPTGS2 | |
| SCHEMBL65650 | 0.80 | TAAR1 (0.57) | GPR52GPR84TAAR1 | |
| SCHEMBL13680808 | 0.80 | EPHX2 (0.38) | — | |
| SCHEMBL13681324 | 0.80 | BCL2 (0.63) | BCL2GPR52ACMSD | |
| SCHEMBL13681341 | 0.80 | HRH3 (0.43) | — | |
| SCHEMBL13680787 | 0.80 | AGXT (0.56) | FFAR1PTPN5DHODHTAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |