Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 3/20 | 0.40 |
| ▸ | GRM5 | P41594 | 3/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27874223 | 0.86 | TP53 (0.52) | CA12CA1CA2CA9KCNH2 | |
| SCHEMBL3859050 | 0.86 | CA12 (0.47) | CA12CA1CA2CA9KCNH2 | |
| SCHEMBL17954217 | 0.82 | FFAR1 (0.57) | FFAR1PTGES | |
| SCHEMBL27941338 | 0.81 | CA12 (0.46) | CA12CA1CA2CA9KCNH2 | |
| SCHEMBL9742616 | 0.80 | ASIC3 (0.51) | CA12CA1CA2CA9KCNH2 | |
| SCHEMBL7503100 | 0.80 | CYP2A6 (0.54) | CA12CA1CA2CA9KCNH2 | |
| SCHEMBL9328231 | 0.80 | CYP2A6 (0.54) | CA12CA1CA2CA9KCNH2 | |
| SCHEMBL30887043 | 0.79 | TP53 (0.41) | FFAR1PTGESGRM5RAPGEF4CYP2D6 | |
| SCHEMBL233927 | 0.78 | CA12 (0.48) | CA12CA1CA2CA9KCNH2 | |
| SCHEMBL16631365 | 0.77 | CA12 (0.47) | CA12CA1CA2CA9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051045-A2 | 3'END CAPS FOR RNAi AGENTS FOR USE IN RNA INTERFERENCE | NOVARTIS AG (CH) | 2015-04-09 | — | — | WO | disclosed |