Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 9/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.48 |
| ▸ | MPO | P05164 | 1/20 | 0.47 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.44 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631915 | 0.91 | KCNMA1 (0.55) | CYP19A1HRH4MPOKCNMA1NPC1 | |
| SCHEMBL18080377 | 0.88 | CYP19A1 (0.48) | CYP19A1HRH4MPOKCNMA1NPC1 | |
| SCHEMBL18081774 | 0.82 | AMY1A (0.33) | MPOAMY1A | |
| SCHEMBL16631690 | 0.81 | L3MBTL1 (0.47) | NPC1RAB9AAMY1AMAOA | |
| SCHEMBL18080399 | 0.80 | KCNMA1 (0.54) | CYP19A1HRH4MPOKCNMA1NPC1 | |
| SCHEMBL16631451 | 0.79 | CYP19A1 (0.53) | CYP19A1HRH4NPC1RAB9AAMY1A | |
| SCHEMBL16631902 | 0.78 | CYP19A1 (0.52) | CYP19A1HRH4NPC1RAB9A | |
| SCHEMBL16631717 | 0.78 | DDB1 (0.38) | MAOAMAOB | |
| SCHEMBL16631387 | 0.78 | MPO (0.51) | CYP19A1HRH4MPOKCNMA1NPC1 | |
| SCHEMBL18081754 | 0.77 | CHRNE (0.35) | CYP19A1KCNMA1AMY1AHSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | CYP19A1 4868/4885HRH4 4824/4885MPO 2859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.