Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081973 | 0.86 | PDE3B (0.32) | PDE3BPDE3AARUSP2TSHR | |
| SCHEMBL16631469 | 0.81 | OPRK1 (0.30) | — | |
| SCHEMBL18081955 | 0.79 | PARP1 (0.30) | — | |
| SCHEMBL16631934 | 0.78 | SMPD3 (0.36) | — | |
| SCHEMBL18081755 | 0.78 | HPGD (0.36) | PDE3BPDE3AUSP2TSHR | |
| SCHEMBL18081917 | 0.75 | PDE3B (0.35) | PDE3BPDE3AUSP2TSHR | |
| SCHEMBL16631454 | 0.74 | TNKS (0.34) | PDE3BPDE3AARUSP2TSHR | |
| SCHEMBL16631455 | 0.74 | PDE3B (0.35) | PDE3BPDE3AUSP2TSHR | |
| SCHEMBL18081810 | 0.74 | DGAT1 (0.42) | — | |
| SCHEMBL18080245 | 0.73 | KDM4E (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | PDE3B 1568/4885PDE3A 1692/4885AR 4464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.