Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631774 | 0.82 | MEN1 (0.33) | SMN1; SMN2ALDH1A1MEN1ABCC4LMNA | |
| SCHEMBL16631758 | 0.81 | LMNA (0.30) | LMNA | |
| SCHEMBL18081828 | 0.80 | KDM4E (0.33) | ALDH1A1 | |
| SCHEMBL16631772 | 0.79 | KMT2A (0.32) | SMN1; SMN2ALDH1A1MEN1ABCC4LMNA | |
| SCHEMBL16631756 | 0.78 | ADORA1 (0.34) | LMNA | |
| SCHEMBL18080608 | 0.76 | — | — | |
| SCHEMBL16631683 | 0.74 | MEN1 (0.30) | MEN1ABCC4LMNAPKMPTGS1 | |
| SCHEMBL18081977 | 0.71 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL16631753 | 0.68 | ADORA2A (0.49) | SMN1; SMN2ALDH1A1MEN1ABCC4LMNA | |
| SCHEMBL18080586 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |