Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631772 | 0.85 | KMT2A (0.32) | MEN1KMT2ALMNAABCC4PKM | |
| SCHEMBL16631683 | 0.83 | MEN1 (0.30) | MEN1KMT2ALMNAABCC4PKM | |
| SCHEMBL16631558 | 0.82 | SMN1; SMN2 (0.32) | MEN1KMT2ALMNAABCC4PKM | |
| SCHEMBL18081845 | 0.80 | KDM4E (0.33) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL16631758 | 0.78 | LMNA (0.30) | LMNA | |
| SCHEMBL18080585 | 0.76 | — | — | |
| SCHEMBL16631756 | 0.72 | ADORA1 (0.34) | LMNA | |
| SCHEMBL16631759 | 0.71 | KMT2A (0.32) | MEN1KMT2ALMNAABCC4PKM | |
| SCHEMBL18081980 | 0.71 | KDM4E (0.31) | KDM4EALDH1A1 | |
| SCHEMBL16631362 | 0.70 | KDM4E (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |