Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | TK1 | P04183 | 3/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | SLC28A1 | O00337 | 1/20 | 0.36 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.36 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | SLC28A3 | Q9HAS3 | 1/20 | 0.36 |
| ▸ | TK2 | O00142 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631724 | 0.79 | LMNA (0.42) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL16631618 | 0.76 | LMNA (0.44) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL16781789 | 0.75 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL18852567 | 0.75 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL18871319 | 0.75 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL16781790 | 0.75 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL16631263 | 0.75 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL16805391 | 0.75 | SLC28A1 (0.46) | SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL16631525 | 0.73 | SLC28A1 (0.41) | SLC28A1SLC28A2SLC29A1SLC28A3 | |
| SCHEMBL17384497 | 0.72 | TK1 (0.37) | LMNASMN1; SMN2ALOX12ADRA1ATK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015196130-A2 | ALTERNATIVE NUCLEIC ACID MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2015-12-23 | — | — | WO | disclosed |
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |