Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | TK1 | P04183 | 3/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.37 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.37 |
| ▸ | TK2 | O00142 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.32 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.32 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.32 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631956 | 0.85 | TK1 (0.37) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL16631586 | 0.79 | LMNA (0.43) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL24420510 | 0.77 | ADRB1 (0.42) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL16631618 | 0.77 | LMNA (0.44) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL27054425 | 0.77 | ADRB1 (0.42) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL16631570 | 0.76 | PYGL (0.44) | LMNASMN1; SMN2CYP1A2CYP3A4TSHR | |
| SCHEMBL16631503 | 0.74 | PYGL (0.38) | LMNASMN1; SMN2BLMPMP22 | |
| SCHEMBL8356828 | 0.74 | ADRB1 (0.38) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL27056556 | 0.72 | KDM4E (0.39) | LMNASMN1; SMN2ALOX12ADRA1ATK1 | |
| SCHEMBL16631377 | 0.71 | PNP (0.36) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |