SCHEMBL16631593

SCHEMBL16631593

O=c1cnc([C@@H]2O[C@H](CO)[C@H](O)C2O)c[nH]1

nearest known ligand 0.43

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PYGL P06737 5/20 0.43
PNP P00491 5/20 0.41
MAPT P10636 1/20 0.41
CDA P32320 1/20 0.41
SLC5A2 P31639 4/20 0.40
UMPS P11172 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16631237 1.00 PYGL (0.43) PYGLPNPMAPTCDASLC5A2
SCHEMBL16631256 0.88 CDA (0.38) PYGLPNPMAPTCDA
SCHEMBL16631435 0.84 PNP (0.35) PYGLPNPMAPTCDASLC5A2
SCHEMBL18079922 0.76 P2RY2 (0.53)
SCHEMBL18079906 0.75 SLC5A2 (0.43) PYGLPNPMAPTSLC5A2
SCHEMBL27614390 0.75 UMPS (0.48) PYGLMAPTSLC5A2UMPS
SCHEMBL16631479 0.74 SLC5A2 (0.45) PYGLPNPMAPTCDASLC5A2
SCHEMBL16781781 0.74 SLC5A2 (0.50) SLC5A2
SCHEMBL5487423 0.74 SLC5A2 (0.50) SLC5A2
SCHEMBL5484694 0.74 SLC5A2 (0.50) SLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015051173-A2 POLYNUCLEOTIDE MOLECULES AND USES THEREOF MODERNA THERAPEUTICS, INC (US) 2015-04-09 WO disclosed