Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631615 | 0.79 | LMNA (0.38) | LMNAL3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL12360794 | 0.79 | LMNA (0.38) | LMNAL3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL14747625 | 0.79 | LMNA (0.38) | LMNAL3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL1417186 | 0.79 | LMNA (0.38) | LMNAL3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL15694284 | 0.79 | LMNA (0.38) | LMNAL3MBTL1TDP1TSHRMAPK1 | |
| SCHEMBL11172596 | 0.78 | CYP2D6 (0.42) | LMNAUSP2TSHRMAPK1 | |
| SCHEMBL4395975 | 0.76 | HTT (0.46) | LMNAUSP2 | |
| SCHEMBL27955401 | 0.75 | — | — | |
| SCHEMBL13737101 | 0.73 | LMNA (0.42) | LMNAL3MBTL1TDP1USP2SLCO1B1 | |
| SCHEMBL792924 | 0.72 | LMNA (0.36) | LMNAL3MBTL1TDP1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190135896-A1 | DERIVATIVES OF ELASTIN-LIKE POLYPEPTIDES AND USES THEREOF | NATIONAL SCIENCE FOUNDATION | 2019-05-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190135896-A1 | DERIVATIVES OF ELASTIN-LIKE POLYPEPTIDES AND USES THEREOF | LNPEP, ELANE, PTMS | LMNA 781/4885L3MBTL1 346/4885TDP1 634/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.