Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | TK1 | P04183 | 7/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TK2 | O00142 | 3/20 | 0.48 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18080421 | 0.86 | KCNMA1 (0.42) | HPGDTK1TK2KCNMA1HRH4 | |
| SCHEMBL16631677 | 0.82 | MAPK1 (0.44) | HPGDTK1MAPK1TK2 | |
| SCHEMBL18081921 | 0.82 | HPGD (0.69) | HPGDTK1MAPK1HRH4 | |
| SCHEMBL16631660 | 0.81 | HPGD (0.52) | HPGDTK1MAPK1TK2 | |
| SCHEMBL16631675 | 0.78 | MAPK1 (0.48) | HPGDTK1MAPK1TK2 | |
| SCHEMBL18081935 | 0.76 | MAPK1 (0.43) | HPGDTK1MAPK1TK2 | |
| SCHEMBL16631458 | 0.75 | TK1 (0.46) | TK1TK2KCNMA1 | |
| SCHEMBL16631915 | 0.74 | KCNMA1 (0.55) | HPGDTK1TK2KCNMA1HRH4 | |
| SCHEMBL3996660 | 0.73 | HPGD (1.00) | HPGDTK1MAPK1 | |
| SCHEMBL18080399 | 0.73 | KCNMA1 (0.54) | HPGDTK1TK2KCNMA1HRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | HPGD 3931/4885TK1 269/4885MAPK1 4185/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.