Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081777 | 0.88 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL18081942 | 0.88 | ALDH1A1 (0.36) | KDM4EALDH1A1 | |
| SCHEMBL18081797 | 0.84 | RAB9A (0.31) | KDM4EALDH1A1 | |
| SCHEMBL18080572 | 0.82 | — | — | |
| SCHEMBL18081793 | 0.78 | KDM4E (0.35) | KDM4EALDH1A1 | |
| SCHEMBL16631914 | 0.75 | ALDH1A1 (0.34) | KDM4EALDH1A1 | |
| SCHEMBL16631760 | 0.74 | HTT (0.32) | KDM4EALDH1A1 | |
| SCHEMBL16631748 | 0.73 | ALDH1A1 (0.37) | KDM4EALDH1A1 | |
| SCHEMBL18080570 | 0.73 | — | — | |
| SCHEMBL18080571 | 0.73 | ALDH1A1 (0.33) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | KDM4E 4689/4885ALDH1A1 4189/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.