Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GJB2 | P29033 | 3/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631585 | 0.82 | GJB2 (0.30) | GJB2 | |
| SCHEMBL16631781 | 0.81 | SMN1; SMN2 (0.33) | ALDH1A1TDP1SMN1; SMN2GJB2 | |
| SCHEMBL18081990 | 0.81 | RARA (0.32) | SMN1; SMN2GJB2RARARARBRARG | |
| SCHEMBL16631959 | 0.76 | GJB2 (0.31) | SMN1; SMN2GJB2 | |
| SCHEMBL16631693 | 0.76 | GJB2 (0.31) | SMN1; SMN2GJB2 | |
| SCHEMBL16631779 | 0.74 | RARA (0.31) | RARARARBRARG | |
| SCHEMBL16631964 | 0.72 | SMN1; SMN2 (0.33) | ALDH1A1TDP1SMN1; SMN2GJB2 | |
| SCHEMBL18081987 | 0.69 | RARA (0.33) | RARARARBRARG | |
| SCHEMBL18081967 | 0.69 | GJB2 (0.33) | GJB2 | |
| SCHEMBL16631666 | 0.69 | GJB2 (0.33) | GJB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |