Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | GJB2 | P29033 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631666 | 0.82 | GJB2 (0.33) | GJB2 | |
| SCHEMBL18081967 | 0.82 | GJB2 (0.33) | GJB2 | |
| SCHEMBL14605405 | 0.81 | SSTR1 (0.34) | GJB2SMN1; SMN2 | |
| SCHEMBL13592729 | 0.81 | SSTR1 (0.34) | GJB2SMN1; SMN2 | |
| SCHEMBL17378597 | 0.81 | SSTR1 (0.32) | GJB2 | |
| SCHEMBL16809051 | 0.81 | SSTR1 (0.32) | GJB2 | |
| SCHEMBL16631719 | 0.81 | GJB2 (0.32) | GJB2 | |
| SCHEMBL16631780 | 0.81 | ALDH1A1 (0.32) | RARARARBRARGGJB2SMN1; SMN2 | |
| SCHEMBL16808981 | 0.79 | SSTR1 (0.33) | GJB2SMN1; SMN2 | |
| SCHEMBL17378673 | 0.79 | SSTR1 (0.33) | GJB2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | RARA 3100/4885RARB 2626/4885RARG 2664/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.