Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 2/20 | 0.34 |
| ▸ | HCAR1 | Q9BXC0 | 3/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18081964 | 0.80 | CRBN (0.36) | CRBNHCAR1PDE3BPDE3A | |
| SCHEMBL13766497 | 0.77 | CRBN (0.32) | CRBN | |
| SCHEMBL18080555 | 0.76 | CRBN (0.33) | CRBNHCAR1 | |
| SCHEMBL16631919 | 0.71 | CRBN (0.34) | CRBNHCAR1 | |
| SCHEMBL13766496 | 0.70 | CRBN (0.38) | CRBN | |
| SCHEMBL18080558 | 0.68 | HCAR1 (0.32) | CRBNHCAR1 | |
| SCHEMBL10867606 | 0.66 | RAB9A (0.52) | PKM | |
| SCHEMBL10874361 | 0.63 | TLR9 (0.40) | PKM | |
| SCHEMBL10867350 | 0.63 | ALDH1A1 (0.39) | — | |
| SCHEMBL4478463 | 0.62 | CRBN (0.38) | CRBNPKMPDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |