Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16631929 | 0.86 | OPRK1 (0.32) | OPRK1KMT2AKDM4E | |
| SCHEMBL18081953 | 0.82 | OPRK1 (0.40) | OPRK1KMT2AMAPTKDM4E | |
| SCHEMBL16631475 | 0.81 | — | — | |
| SCHEMBL18080546 | 0.81 | OPRK1 (0.38) | OPRK1KMT2A | |
| SCHEMBL16631935 | 0.79 | GRIN2D (0.31) | — | |
| SCHEMBL18081976 | 0.79 | OPRK1 (0.32) | OPRK1KMT2AKDM4E | |
| SCHEMBL18081785 | 0.72 | — | — | |
| SCHEMBL18081969 | 0.72 | L3MBTL1 (0.33) | OPRK1KMT2AMAPT | |
| SCHEMBL16631450 | 0.72 | MAPT (0.38) | OPRK1KMT2AMAPT | |
| SCHEMBL16631469 | 0.72 | OPRK1 (0.30) | OPRK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC. (US) | 2016-09-15 | — | — | US | disclosed |
| WO-2015051173-A2 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | MODERNA THERAPEUTICS, INC (US) | 2015-04-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264614-A1 | POLYNUCLEOTIDE MOLECULES AND USES THEREOF | POLRMT, POLN, NSUN3 | OPRK1 1659/4885KMT2A 3598/4885MAPT 3290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.