Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.51 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632031 | 0.82 | NAMPT (0.45) | NAMPTCYP19A1CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL28150000 | 0.79 | MAPT (0.54) | NAMPTCYP19A1CYP11B1CYP11B2CYP2A6 | |
| SCHEMBL28148758 | 0.77 | CYP1A2 (0.56) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| Hydrochloric Acid SCHEMBL6891778 | 0.69 | CYP19A1 (0.43) | CYP19A1CYP11B1 | |
| Hydrochloric Acid SCHEMBL6891758 | 0.69 | CYP19A1 (0.43) | CYP19A1CYP11B1 | |
| SCHEMBL15531850 | 0.68 | NAMPT (1.00) | NAMPT | |
| SCHEMBL28140205 | 0.68 | CYP11B1 (0.63) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL1024261 | 0.67 | CYP11B1 (0.84) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| SCHEMBL19742865 | 0.66 | CYP11B1 (0.68) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 | |
| Hydrochloric Acid SCHEMBL1775141 | 0.65 | CYP11B1 (0.81) | CYP19A1CYP11B1CYP11B2CYP2A6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10696692-B2 | Amido-benzyl sulfone and sulfoxide derivates | Valo Health, LLC | 2020-06-30 | — | — | US | claimed |
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | VALO HEALTH, INC. | 2015-04-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10696692-B2 | Amido-benzyl sulfone and sulfoxide derivates | STS, SQOR, SULT1E1 | NAMPT 459/4885CYP19A1 2817/4885CYP11B1 579/4885 |
| US-20150104384-A1 | AMIDO-BENZYL SULFONE AND SULFOXIDE DERIVATIVES | STS, SULT1E1, CBS | NAMPT 759/4885CYP19A1 2466/4885CYP11B1 373/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.