Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 9/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16632606 | 0.92 | L3MBTL1 (0.39) | L3MBTL1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16634456 | 0.90 | L3MBTL1 (0.44) | L3MBTL1DUTTSHRNPSR1CYP19A1 | |
| SCHEMBL16634455 | 0.89 | L3MBTL1 (0.35) | L3MBTL1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16634453 | 0.81 | L3MBTL1 (0.39) | L3MBTL1MEN1KMT2ADUTHTR2C | |
| SCHEMBL16632387 | 0.81 | L3MBTL1 (0.43) | L3MBTL1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16632569 | 0.81 | L3MBTL1 (0.37) | L3MBTL1MEN1MAPTKMT2ADUT | |
| SCHEMBL16632519 | 0.78 | L3MBTL1 (0.39) | L3MBTL1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16632610 | 0.78 | L3MBTL1 (0.40) | L3MBTL1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16632609 | 0.77 | L3MBTL1 (0.40) | L3MBTL1MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL16632682 | 0.77 | L3MBTL1 (0.47) | L3MBTL1KMT2ADUTTSHRCYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382245-B2 | Compounds and methods for treating HIV infections | YALE UNIVERSITY (US) | 2016-07-05 | — | — | US | disclosed |
| US-20150105351-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105351-A1 | COMPOUNDS AND METHODS FOR TREATING HIV INFECTIONS | POLM, POLRMT, DHFR | L3MBTL1 879/4885MEN1 4881/4885ALDH1A1 1200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.