Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ELANE | P08246 | 5/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | PLAU | P00749 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1664651 | 0.81 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL25372714 | 0.79 | ALDH1A1 (0.45) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL22148316 | 0.68 | ALDH1A1 (0.54) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL1663023 | 0.68 | HTR3A (0.39) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL1662930 | 0.67 | KDM4E (0.36) | ALDH1A1KMT2AMAPTKDM4ESMN1; SMN2 | |
| SCHEMBL18366709 | 0.67 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL1663228 | 0.67 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL1663371 | 0.67 | EGFR (0.43) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| Methane SCHEMBL1664900 | 0.66 | MCL1 (0.39) | ELANEF2PLAU | |
| SCHEMBL1663213 | 0.66 | ALDH1A1 (0.41) | ALDH1A1MEN1KMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |