Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17653503 | 0.77 | HTR2A (0.48) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL29202636 | 0.77 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL27281539 | 0.76 | GABRA1 (0.38) | GABRA1GABRB2MEN1KMT2A | |
| SCHEMBL27282956 | 0.72 | GABRA1 (0.49) | GABRA1GABRB2MEN1KMT2AALDH1A1 | |
| SCHEMBL27285538 | 0.70 | HPGD (0.43) | GABRA1GABRB2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL28680618 | 0.70 | CYP1A2 (0.48) | GABRA1GABRB2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL10630320 | 0.70 | HPRT1 (0.52) | GABRA1GABRB2ALDH1A1HSD17B10TSHR | |
| SCHEMBL11126357 | 0.69 | KMT2A (0.49) | MEN1KMT2AALDH1A1HPGDHSD17B10 | |
| SCHEMBL19224313 | 0.69 | LMNA (0.42) | MEN1KMT2AL3MBTL1KDM4ECYP1A2 | |
| SCHEMBL5393655 | 0.69 | KMT2A (0.49) | MEN1KMT2AALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |