SCHEMBL16633142

SCHEMBL16633142

c1ccc(-c2cccc(-c3ccc4ccc5c(-c6ccc(N(c7ccccc7-c7ccccc7)c7ccccc7-c7ccccc7)cc6)ccc6ccc3c4c65)c2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
HSD17B1 P14061 2/20 0.33
HSD17B2 P37059 2/20 0.33
MEN1 O00255 1/20 0.33
APAF1 O14727 1/20 0.33
NPC1 O15118 1/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
THRB P10828 1/20 0.33
XBP1 P17861 1/20 0.33
PTBP1 P26599 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
GALK1 P51570 1/20 0.33
BLM P54132 1/20 0.33
SMAD3 P84022 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16641953 0.97 CA12 (0.34) CA12CA1CA2CA9HSD17B1
SCHEMBL16641958 0.92 TNF (0.32) CRHR1CDK4CCND1TNF
SCHEMBL16639338 0.90 RXRA (0.31) MEN1APAF1NPC1LMNAMAPT
SCHEMBL16641952 0.90 RXRA (0.31) MEN1APAF1NPC1LMNAMAPT
SCHEMBL16639634 0.90 RXRA (0.31) MEN1APAF1NPC1LMNAMAPT
SCHEMBL16641969 0.90 HSD17B1 (0.36) CA12CA1CA2CA9HSD17B1
SCHEMBL16639340 0.89 CYP1A2 (0.35) CA12CA1CA2CA9HSD17B1
SCHEMBL16639641 0.89
SCHEMBL16639278 0.88 RXRA (0.31) MAPTL3MBTL1CDK4CCND1TNF
SCHEMBL16639279 0.88 RXRA (0.31) MAPTL3MBTL1CDK4CCND1TNF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-9293712-B2 Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same UNIVERSAL DISPLAY CORPORATION (US) 2016-03-22 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed
US-20150102321-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION 2015-04-16 US disclosed