⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16641958 | 0.94 | TNF (0.32) | — | |
| SCHEMBL16639326 | 0.93 | CRHR1 (0.33) | — | |
| SCHEMBL16639338 | 0.93 | RXRA (0.31) | — | |
| SCHEMBL16641952 | 0.93 | RXRA (0.31) | — | |
| SCHEMBL16639634 | 0.93 | RXRA (0.31) | — | |
| SCHEMBL16639341 | 0.90 | CASP3 (0.30) | — | |
| SCHEMBL16639279 | 0.90 | RXRA (0.31) | — | |
| SCHEMBL16639278 | 0.90 | RXRA (0.31) | — | |
| SCHEMBL29636227 | 0.90 | CASP3 (0.30) | — | |
| SCHEMBL16633142 | 0.89 | CA12 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9293712-B2 | Disubstituted pyrene compounds with amino group containing ortho aryl group and devices containing the same | UNIVERSAL DISPLAY CORPORATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20150102290-A1 | DISUBSTITUTED PYRENE COMPOUNDS WITH AMINO GROUP CONTAINING ORTHO ARYL GROUP | UNIVERSAL DISPLAY CORPORATION (US) | 2015-04-16 | — | — | US | disclosed |
| US-20150102321-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION | 2015-04-16 | — | — | US | disclosed |