Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1291771 | 0.84 | PTGS1 (0.38) | ALDH1A1GAAHPGDNPSR1MEN1 | |
| SCHEMBL23809790 | 0.74 | ALDH1A1 (0.38) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL10058036 | 0.70 | POLB (0.38) | — | |
| SCHEMBL1292112 | 0.70 | NPC1 (0.39) | ALDH1A1NPSR1NPC1RAB9AMEN1 | |
| SCHEMBL4147982 | 0.68 | POLB (0.36) | HPGDPTGS1PTGS2HTTCYP1A2 | |
| SCHEMBL25726179 | 0.68 | TSHR (0.50) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL13144262 | 0.68 | ALDH1A1 (0.45) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL19122234 | 0.68 | PTGS1 (0.39) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL13144265 | 0.67 | ALDH1A1 (0.47) | ALDH1A1GAAUSP2PKMHPGD | |
| SCHEMBL2618697 | 0.67 | CYP2D6 (0.53) | NPSR1MEN1KMT2ACYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2624811-B1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH & CIE (CH) | 2017-06-21 | — | — | EP | disclosed |
| EP-2624811-B1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH & CIE (CH) | 2017-06-21 | — | — | EP | disclosed |
| US-9382500-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2016-07-05 | — | — | US | disclosed |
| US-9382500-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2016-07-05 | — | — | US | disclosed |
| US-9382500-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2016-07-05 | — | — | US | disclosed |
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2015-06-04 | — | — | US | disclosed |
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2015-06-04 | — | — | US | disclosed |
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2015-06-04 | — | — | US | disclosed |
| US-8987188-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2015-03-24 | — | — | US | disclosed |
| US-8987188-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2015-03-24 | — | — | US | disclosed |
| US-8987188-B2 | Benzodioxole derivatives as watery odorants | FIRMENICH SA (CH) | 2015-03-24 | — | — | US | disclosed |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2013-10-31 | — | — | US | disclosed |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2013-10-31 | — | — | US | disclosed |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2013-10-31 | — | — | US | disclosed |
| WO-2012045646-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | FIRMENICH SA (CH) | 2012-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150152352-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | TRPA1, BBOX1, PAOX | ALDH1A1 452/4885GAA 4586/4885USP2 3509/4885 |
| US-20130288947-A1 | BENZODIOXOLE DERIVATIVES AS WATERY ODORANTS | BBOX1, CBR3, CBR1 | ALDH1A1 789/4885GAA 4804/4885USP2 2912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.