Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.46 |
| ▸ | MMP9 | P14780 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 1/20 | 0.37 |
| ▸ | TOP2A | P11388 | 2/20 | 0.37 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ANXA2 | P07355 | 1/20 | 0.36 |
| ▸ | S100A10 | P60903 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14910663 | 0.86 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9ATHRB | |
| SCHEMBL14911308 | 0.86 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9ATHRB | |
| SCHEMBL14910664 | 0.86 | KMT2A (0.49) | KMT2AMEN1NPC1RAB9ATHRB | |
| SCHEMBL2506939 | 0.82 | FFAR1 (0.48) | MMP2MMP9KMT2AMEN1NPC1 | |
| SCHEMBL16633119 | 0.79 | SLC6A4 (0.47) | KMT2AMEN1OPRM1OPRK1 | |
| SCHEMBL16633980 | 0.79 | ALDH1A1 (0.41) | MMP2MMP9PDE2AEPHX1SERPINE1 | |
| SCHEMBL16634078 | 0.78 | EPHX1 (0.40) | MMP2MMP9PDE2AEPHX1SERPINE1 | |
| SCHEMBL16633204 | 0.77 | MMP2 (0.40) | MMP2MMP9OPRM1PDE2AEPHX1 | |
| SCHEMBL14910738 | 0.77 | KMT2A (0.43) | MMP2MMP9KMT2AMEN1NPC1 | |
| SCHEMBL14910736 | 0.77 | KMT2A (0.43) | MMP2MMP9KMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469637-B2 | Nitrogenated heterocyclic compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-10-18 | — | — | US | disclosed |
| US-20150105373-A1 | NITROGENATED HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-04-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105373-A1 | NITROGENATED HETEROCYCLIC COMPOUND | PDE2A, PDE5A, PDE3A | MMP2 860/4885MMP9 474/4885KMT2A 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.