Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.40 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | F13A1 | P00488 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 1/20 | 0.38 |
| ▸ | TGM1 | P22735 | 1/20 | 0.38 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1663275 | 0.83 | GALR2 (0.43) | NR1H2PDE4BGALR2GALR1ESR2 | |
| SCHEMBL1584703 | 0.83 | CPS1 (0.46) | NR1H2P2RX7KDM4EMAPTGPR119 | |
| SCHEMBL1662799 | 0.82 | NR1H2 (0.41) | NR1H2PDE4BPDE7AP2RX7RBP4 | |
| SCHEMBL4537183 | 0.81 | P2RX7 (0.55) | P2RX7MKNK1 | |
| SCHEMBL1663380 | 0.81 | PTGDR2 (0.44) | FFAR4P2RX7RBP4MAPTGPR119 | |
| SCHEMBL1662960 | 0.81 | P2RX7 (0.44) | NR1H2PDE4BPDE7AP2RX7ESR2 | |
| SCHEMBL22650493 | 0.81 | NR1H2 (0.54) | NR1H2PDE4BPDE7AP2RX7ESR2 | |
| SCHEMBL29507776 | 0.81 | NR1H2 (0.54) | NR1H2PDE4BPDE7AP2RX7ESR2 | |
| SCHEMBL1583488 | 0.79 | MEN1 (0.51) | NR1H2P2RX7KDM4EMAPTSCN9A | |
| SCHEMBL30734152 | 0.79 | MEN1 (0.51) | NR1H2P2RX7KDM4EMAPTSCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011050284-A1 | PYRAZOLYLPYRIDINE ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2011-04-28 | — | — | WO | disclosed |