SCHEMBL7898955

SCHEMBL7898955

CCN(CC)CCNCCC[Si](C)(OC)OC

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 1/20 0.37
CHRM2 P08172 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.32
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28356688 0.84 PAOX (0.38) PAOXCHRM2SMN1; SMN2CYP1A2CYP2D6
SCHEMBL537901 0.82 CYP2C19 (0.33) CYP1A2
SCHEMBL28438294 0.81 CYP2C9 (0.47) PAOXSMN1; SMN2
SCHEMBL379299 0.81 ALDH1A1 (0.33)
SCHEMBL1638782 0.80 CYP2C19 (0.32) CYP1A2
SCHEMBL7603361 0.80 KMT2A (0.43) CYP1A2CYP2D6CYP3A4
SCHEMBL16633974 0.80 PAOX (0.38) PAOXCHRM2SMN1; SMN2
SCHEMBL379353 0.79 ALDH1A1 (0.36) CHRM2
SCHEMBL12002833 0.79 PAOX (0.41) PAOXCYP1A2
SCHEMBL272668 0.79 TSHR (0.44) PAOXCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6201058-B1 POLYMERS WITH REVERSE CHANGES, TEMPERATURE SENSITIVE WACKER-CHEMIE GMBH (DE) 2001-03-13 US disclosed