SCHEMBL16634417

SCHEMBL16634417

O=[C]c1ccc(S(=O)(=O)NC(=O)c2ccccc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 3/20 0.67
FLT4 P35916 3/20 0.67
KDR P35968 3/20 0.67
MEN1 O00255 1/20 0.67
LMNA P02545 1/20 0.67
KMT2A Q03164 1/20 0.67
L3MBTL1 Q9Y468 1/20 0.67
KAT6A Q92794 1/20 0.54
PTGS2 P35354 2/20 0.54
BCL2L1 Q07817 5/20 0.54
MCL1 Q07820 5/20 0.54
PTGS1 P23219 1/20 0.53
HTT P42858 1/20 0.51
P4HTM Q9NXG6 3/20 0.50
PTGES O14684 1/20 0.49
CYP2C9 P11712 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7319450 0.94 FLT1 (0.58) FLT1FLT4KDRMEN1LMNA
SCHEMBL7209929 0.84 FLT1 (0.79) FLT1FLT4KDRL3MBTL1PTGS2
SCHEMBL7213397 0.84 PTGS2 (0.64) FLT1FLT4KDRMEN1LMNA
SCHEMBL9185479 0.84 FLT1 (0.55) FLT1FLT4KDRMEN1LMNA
SCHEMBL174010 0.84 FLT1 (0.77) FLT1FLT4KDRMEN1LMNA
SCHEMBL29011132 0.83 FLT1 (0.74) FLT1FLT4KDRMEN1LMNA
Potassium SCHEMBL30358590 0.83 FLT1 (0.74) FLT1FLT4KDRMEN1LMNA
SCHEMBL8424044 0.81 FLT1 (0.73) FLT1FLT4KDRMEN1LMNA
SCHEMBL5931288 0.81 FLT1 (0.71) FLT1FLT4KDRMEN1LMNA
SCHEMBL5931087 0.80 PTGS2 (0.71) FLT1FLT4KDRMEN1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3055292-B1 PROCESS FOR PREPARING 4-[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES BAYER CROPSCIENCE AG (DE) 2017-08-16 EP claimed
EP-3055292-A1 PROCESS FOR PREPARING 4-[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES Bayer CropScience Aktiengesellschaft (DE) 2016-08-17 EP disclosed
WO-2015052156-A1 PROCESS FOR PREPARING 4-[[(BENZOYL)AMINO]SULPHONYL]BENZOYL CHLORIDES AND PREPARATION OF ACYLSULPHAMOYLBENZAMIDES BAYER CROPSCIENCE AG (DE) 2015-04-16 WO disclosed