SCHEMBL174010

SCHEMBL174010

O=C(NS(=O)(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FLT1 P17948 2/20 0.77
FLT4 P35916 2/20 0.77
KDR P35968 2/20 0.77
MEN1 O00255 2/20 0.77
KMT2A Q03164 2/20 0.77
LMNA P02545 1/20 0.77
L3MBTL1 Q9Y468 1/20 0.77
PTGS2 P35354 4/20 0.70
PTGS1 P23219 2/20 0.69
KAT6A Q92794 1/20 0.67
P4HTM Q9NXG6 3/20 0.65
KDM4E B2RXH2 1/20 0.62
HPGD P15428 1/20 0.61
EGFR P00533 1/20 0.59
BCL2L1 Q07817 1/20 0.59
MCL1 Q07820 1/20 0.59
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
MMP1 P03956 1/20 0.59
MMP2 P08253 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium SCHEMBL30358590 0.98 FLT1 (0.74) FLT1FLT4KDRMEN1KMT2A
SCHEMBL29011132 0.98 FLT1 (0.74) FLT1FLT4KDRMEN1KMT2A
SCHEMBL5931288 0.96 FLT1 (0.71) FLT1FLT4KDRMEN1KMT2A
Benzenesulfonamide SCHEMBL11827648 0.91 MEN1 (0.71) FLT1FLT4KDRMEN1KMT2A
SCHEMBL7278965 0.90 P4HTM (0.65) FLT1FLT4KDRMEN1KMT2A
SCHEMBL31331608 0.89 BCL2L1 (0.75) FLT1FLT4KDRMEN1KMT2A
SCHEMBL8424044 0.89 FLT1 (0.73) FLT1FLT4KDRMEN1KMT2A
SCHEMBL24347999 0.87 PTGS2 (0.67) FLT1FLT4KDRMEN1KMT2A
SCHEMBL8660071 0.87 MEN1 (0.87) FLT1FLT4KDRMEN1KMT2A
SCHEMBL5931087 0.87 PTGS2 (0.71) FLT1FLT4KDRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1163 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111295382-B Bridged bicyclic compounds as farnesyl ester X receptor modulators 百时美施贵宝公司 2024-02-02 CN claimed
CN-114059090-B Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative 福州大学 2023-11-21 CN claimed
WO-2023122938-A1 HETEROCYCLIC COMPOUNDS AS SHP2 INHIBITORS, COMPOSITIONS COMPRISING THE HETEROCYCLIC COMPOUND, AND METHODS OF USE THEREOF JS INNOMED HOLDINGS LTD. (KY) 2023-07-06 WO claimed
CN-114059090-A Preparation method of benzo [ e ] [1,4,3] oxathiazine-1, 1-dioxide derivative 福州大学 2022-02-18 CN claimed
CN-111657289-B Special herbicide composition for flowers and preparation, application and control method thereof 合力科技股份有限公司 2021-12-17 CN claimed
CN-111657289-A Special herbicide composition for flowers and preparation, application and control method thereof 合力科技股份有限公司 2020-09-15 CN claimed
US-10701934-B2 Synergistic weed control from applications of penoxsulam and benzobicyclon or clomazone and benzobicyclon DOW AGROSCIENCES, LLC (US) 2020-07-07 US claimed
EP-3626241-A1 N-BENZENESULFONYLBENZAMIDE COMPOUND FOR INHIBITING BCL-2 PROTEIN AND COMPOSITION AND USE THEREOF Shenzhen Targetrx, Inc. (CN) 2020-03-25 EP claimed
EP-2592929-B1 SOLID HERBICIDE COMPOSITIONS WITH BUILT-IN ADJUVANT DOW AGROSCIENCES LLC (US) 2020-03-18 EP claimed
CN-106957315-B N- replaces benzenesulfonyl-azaindole oxybenzamide class compound and its prepares the purposes of drug 中国人民解放军第二军医大学 2019-08-13 CN claimed
EP-0399732-B1 Benzimidazole derivatives ZENECA LTD (GB) 1995-07-26 EP claimed
EP-0542556-B1 Thermosensitive recording material NEW OJI PAPER CO LTD (JP) 1995-07-19 EP claimed
US-5314859-A Thermosensitive recording material OJI PAPER CO., LTD. (JP) 1994-05-24 US claimed
EP-0542556-A1 Thermosensitive recording material NEW OJI PAPER CO., LTD. (JP) 1993-05-19 EP claimed
EP-0204571-B1 SELECTED DIFLUORO DERIVATIVES ICI AMERICAS INC. (US) 1992-01-22 EP claimed
EP-0399732-A1 Benzimidazole derivatives ZENECA LIMITED (GB) 1990-11-28 EP claimed
EP-0043630-B1 IMPROVED PROCESS FOR THE SILYLATION OF ORGANIC COMPOUNDS WITH 1,1,1-TRIMETHYL-N-(TRIMETHYLSILYL)SILANAMINE BY MEANS OF CATALYSIS WITH CERTAIN NITROGEN CONTAINING COMPOUNDS GIST-BROCADES N.V. (NL) 1986-01-08 EP claimed
US-4400509-A WITH HEXAMETHYLDISILANE WITH AN ORGANONITROGEN CATALYST GIST-BROCADES N.V. (NL) 1983-08-23 US claimed
EP-0043630-A2 Improved process for the silylation of organic compounds with 1,1,1-trimethyl-N-(trimethylsilyl)silanamine by means of catalysis with certain nitrogen containing compounds GIST-BROCADES N.V. (NL) 1982-01-13 EP claimed
US-4032413-A ELECTROPLATING BATH AND METHOD FOR THE ELECTRODEPOSITION OF BRIGHT ALUMINUM COATINGS SIEMENS AKTIENGESELLSCHAFT (DT) 1977-06-28 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10701934-B2 Synergistic weed control from applications of penoxsulam and benzobicyclon or clomazone and benzobicyclon NOTUM, PAOX, BROX FLT1 4108/4885FLT4 3601/4885KDR 3173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.