Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 12/20 | 0.57 |
| ▸ | F13A1 | P00488 | 2/20 | 0.49 |
| ▸ | TGM1 | P22735 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TGM3 | Q08188 | 1/20 | 0.49 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.43 |
| ▸ | TEK | Q02763 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30568681 | 0.83 | TGM2 (0.65) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL19386525 | 0.83 | TGM2 (0.65) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL28546969 | 0.80 | TGM2 (0.61) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL2554377 | 0.80 | ALDH1A1 (0.56) | — | |
| SCHEMBL29956001 | 0.80 | ALDH1A1 (0.56) | — | |
| SCHEMBL1369735 | 0.79 | TGM2 (0.56) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL15651709 | 0.79 | TGM2 (0.59) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL16523986 | 0.79 | TGM2 (0.59) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL16634497 | 0.78 | TGM2 (0.46) | TGM2F13A1TGM1LMNATGM3 | |
| SCHEMBL22895500 | 0.77 | TGM2 (0.57) | TGM2F13A1TGM1LMNATGM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403568-B | Quinazoline Aurora A covalent inhibitor and preparation method and application thereof | 中山大学 | 2023-09-29 | — | — | CN | disclosed |
| CN-115403568-A | Quinazoline Aurora A covalent inhibitor and preparation method and application thereof | 中山大学 | 2022-11-29 | — | — | CN | disclosed |
| US-10088476-B2 | Volume response sensors having analyte controlled reversible crosslinking | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-10-02 | — | — | US | disclosed |
| US-20160252505-A1 | VOLUME RESPONSE SENSORS HAVING ANALYTE CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI S (US) | 2016-09-01 | — | — | US | disclosed |
| WO-2015053975-A1 | VOLUME RESPONSE SENSORS HAVING CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-16 | — | — | WO | disclosed |