SCHEMBL1369735

SCHEMBL1369735

C=CC(=O)Nc1ccc(F)c(B(O)O)c1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 12/20 0.56
F13A1 P00488 2/20 0.47
TGM1 P22735 2/20 0.47
LMNA P02545 1/20 0.47
TGM3 Q08188 1/20 0.47
GSTO1 P78417 1/20 0.44
EGFR P00533 5/20 0.44
ERBB2 P04626 2/20 0.44
BTK Q06187 1/20 0.44
NOX1 Q9Y5S8 1/20 0.42
ITK Q08881 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7621031 0.82 TGM2 (0.65) TGM2F13A1TGM1LMNATGM3
SCHEMBL16523986 0.81 TGM2 (0.59) TGM2F13A1TGM1LMNATGM3
SCHEMBL4547745 0.80 MEN1 (0.49)
SCHEMBL16634474 0.79 TGM2 (0.57) TGM2F13A1TGM1LMNATGM3
SCHEMBL17685580 0.79 TGM2 (0.49) TGM2F13A1TGM1LMNATGM3
SCHEMBL17685578 0.79 TGM2 (0.49) TGM2F13A1TGM1LMNATGM3
SCHEMBL29767497 0.79 TGM2 (0.61) TGM2F13A1TGM1LMNATGM3
SCHEMBL20500840 0.79 TGM2 (0.61) TGM2F13A1TGM1LMNATGM3
SCHEMBL17685582 0.79 EGFR (0.50) TGM2F13A1TGM1LMNATGM3
SCHEMBL29956038 0.78 TGM2 (0.47) TGM2F13A1TGM1LMNATGM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1601999-B1 Holographic sensor and its use SMART HOLOGRAMS LTD (GB) 2013-04-24 EP claimed
US-20080214912-A1 Blood Glucose Monitoring System And Method GLUCOSE SENSING TECHNOLOGIES, LLC (US) 2008-09-04 US claimed
US-20060063038-A1 Holographic sensor CAMBRIDGE ENTERPRISE LTD (GB) 2006-03-23 US claimed
EP-1601999-A1 HOLOGRAPHIC SENSOR Smart Holograms Limited (GB) 2005-12-07 EP claimed
WO-2004081624-A1 HOLOGRAPHIC SENSOR SMART HOLOGRAMS LIMITED (GB) 2004-09-23 WO claimed
US-10088476-B2 Volume response sensors having analyte controlled reversible crosslinking THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2018-10-02 US disclosed
US-20160252505-A1 VOLUME RESPONSE SENSORS HAVING ANALYTE CONTROLLED REVERSIBLE CROSSLINKING THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI S (US) 2016-09-01 US disclosed
WO-2015053975-A1 VOLUME RESPONSE SENSORS HAVING CONTROLLED REVERSIBLE CROSSLINKING THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2015-04-16 WO disclosed
EP-1601999-B1 Holographic sensor and its use SMART HOLOGRAMS LTD (GB) 2013-04-24 EP disclosed
US-8241574-B2 Ophthalmic device comprising a holographic sensor SMART HOLOGRAMS LIMITED (GB) 2012-08-14 US disclosed
US-20120107944-A1 Holographic Sensor LOWE CHRISTOPHER ROBIN (GB) 2012-05-03 US disclosed
US-20110286064-A1 OPHTHALMIC DEVICE COMPRISING A HOLOGRAPHIC SENSOR BURLES BARRY (GB) 2011-11-24 US disclosed
US-8048680-B2 Holographic sensor SMART HOLOGRAMS LIMITED (GB) 2011-11-01 US disclosed
US-7998412-B2 Ophthalmic device comprising a holographic sensor SMART HOLOGRAMS LIMITED (GB) 2011-08-16 US disclosed
US-20090021697-A1 Ophthalmic Device Comprising a Holographic Sensor SMART HOLOGRAMS LIMITED (GB) 2009-01-22 US disclosed
US-20080214912-A1 Blood Glucose Monitoring System And Method GLUCOSE SENSING TECHNOLOGIES, LLC (US) 2008-09-04 US disclosed
US-20060063038-A1 Holographic sensor CAMBRIDGE ENTERPRISE LTD (GB) 2006-03-23 US disclosed
EP-1601999-A1 HOLOGRAPHIC SENSOR Smart Holograms Limited (GB) 2005-12-07 EP disclosed
WO-2004081624-A1 HOLOGRAPHIC SENSOR SMART HOLOGRAMS LIMITED (GB) 2004-09-23 WO disclosed