SCHEMBL16634504

SCHEMBL16634504

C=CC(=O)Nc1ccc(B(O)O)cc1F

nearest known ligand 0.44

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.44
CYP2C19 P33261 1/20 0.44
TGM2 P21980 5/20 0.44
EGFR P00533 5/20 0.40
LMNA P02545 4/20 0.38
BTK Q06187 3/20 0.38
ITK Q08881 1/20 0.38
F13A1 P00488 2/20 0.38
TGM1 P22735 2/20 0.38
KDR P35968 3/20 0.38
JAK2 O60674 1/20 0.37
JAK3 P52333 1/20 0.37
BRD4 O60885 1/20 0.37
TGM3 Q08188 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14750323 0.88 BTK (0.46) TGM2EGFRBTKITK
SCHEMBL15356552 0.81 TGM2 (0.40) ALDH1A1CYP2C19TGM2LMNABTK
SCHEMBL28900184 0.81 TGM2 (0.44) ALDH1A1TGM2EGFRLMNAF13A1
SCHEMBL28900078 0.81 TTR (0.45) TGM2EGFRLMNABTKF13A1
SCHEMBL28900163 0.81 BTK (0.47) CYP2C19TGM2EGFRBTKKDR
SCHEMBL29505769 0.80 ALDH1A1 (0.66) ALDH1A1CYP2C19TGM2EGFRLMNA
SCHEMBL8549226 0.80 ALDH1A1 (0.66) ALDH1A1CYP2C19TGM2EGFRLMNA
SCHEMBL23795788 0.79 HDAC1 (0.55) ALDH1A1
SCHEMBL30881591 0.79 HDAC1 (0.55) ALDH1A1
SCHEMBL1090234 0.79 KIF11 (0.54) ALDH1A1CYP2C19EGFRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12447133-B2 Composition and device for preventing hypoglycemia and use thereof THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2025-10-21 US claimed
US-20210393543-A1 COMPOSITION AND DEVICE FOR PREVENTING HYPOGLYCEMIA AND USE THEREOF THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2021-12-23 US claimed
EP-3876908-A1 COMPOSITION AND DEVICE FOR PREVENTING HYPOGLYCEMIA AND USE THEREOF The Governing Council Of The University Of Toronto (CA) 2021-09-15 EP claimed
US-12447133-B2 Composition and device for preventing hypoglycemia and use thereof THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2025-10-21 US disclosed
EP-4601730-A1 COMPOSITIONS FOR GLUCOSE-RESPONSIVE DRUG DELIVERY SYSTEMS VIA MULTIFUNCTIONAL HYDROGEL-BASED MICRONEEDLE The Governing Council of the University of Toronto (CA) 2025-08-20 EP disclosed
WO-2024077402-A1 COMPOSITIONS FOR GLUCOSE-RESPONSIVE DRUG DELIVERY SYSTEMS VIA MULTIFUNCTIONAL HYDROGEL-BASED MICRONEEDLE THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2024-04-18 WO disclosed
US-20210393543-A1 COMPOSITION AND DEVICE FOR PREVENTING HYPOGLYCEMIA AND USE THEREOF THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO (CA) 2021-12-23 US disclosed
EP-3876908-A1 COMPOSITION AND DEVICE FOR PREVENTING HYPOGLYCEMIA AND USE THEREOF The Governing Council Of The University Of Toronto (CA) 2021-09-15 EP disclosed
US-10088476-B2 Volume response sensors having analyte controlled reversible crosslinking THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2018-10-02 US disclosed
US-20160252505-A1 VOLUME RESPONSE SENSORS HAVING ANALYTE CONTROLLED REVERSIBLE CROSSLINKING THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI S (US) 2016-09-01 US disclosed
WO-2015053975-A1 VOLUME RESPONSE SENSORS HAVING CONTROLLED REVERSIBLE CROSSLINKING THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2015-04-16 WO disclosed