Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 9/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634494 | 0.89 | TGM2 (0.41) | TGM2MTNR1AMTNR1BP2RX7PSMB5 | |
| SCHEMBL12468919 | 0.82 | TGM2 (0.45) | TGM2MTNR1AMTNR1B | |
| SCHEMBL16634646 | 0.79 | TGM2 (0.45) | TGM2CYP2D6CYP2C19 | |
| SCHEMBL16634568 | 0.79 | TGM2 (0.46) | TGM2 | |
| SCHEMBL15938679 | 0.77 | TGM2 (0.43) | TGM2MTNR1AMTNR1B | |
| SCHEMBL19171260 | 0.76 | HTT (0.56) | P2RX7 | |
| SCHEMBL29957341 | 0.75 | KDM4A (0.42) | — | |
| SCHEMBL16634491 | 0.75 | TGM2 (0.51) | TGM2CYP2C19LIPE | |
| SCHEMBL16634499 | 0.74 | TGM2 (0.51) | TGM2PSMB5 | |
| SCHEMBL30949051 | 0.73 | TGM2 (0.53) | TGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10088476-B2 | Volume response sensors having analyte controlled reversible crosslinking | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-10-02 | — | — | US | disclosed |
| US-20160252505-A1 | VOLUME RESPONSE SENSORS HAVING ANALYTE CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI S (US) | 2016-09-01 | — | — | US | disclosed |
| WO-2015053975-A1 | VOLUME RESPONSE SENSORS HAVING CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-16 | — | — | WO | disclosed |