Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.36 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12784726 | 0.83 | TGM2 (0.58) | TGM2MMP13 | |
| SCHEMBL27616665 | 0.78 | TGM2 (0.55) | TGM2 | |
| SCHEMBL30949051 | 0.76 | TGM2 (0.53) | TGM2BTKEPHX2EGFRPOLB | |
| SCHEMBL732934 | 0.76 | TGM2 (0.81) | TGM2ALDH1A1LMNA | |
| SCHEMBL16634475 | 0.75 | TGM2 (0.65) | TGM2ALDH1A1LMNA | |
| SCHEMBL1444381 | 0.75 | GRM2 (0.46) | EPHX2NR1H4 | |
| SCHEMBL5071229 | 0.75 | TGM2 (0.69) | TGM2ALDH1A1POLBLMNA | |
| SCHEMBL1369735 | 0.75 | TGM2 (0.56) | TGM2BTKEGFRLMNA | |
| SCHEMBL16634494 | 0.74 | TGM2 (0.41) | TGM2PSMB5ALDH1A1FGFR1FGFR4 | |
| SCHEMBL16634557 | 0.74 | TGM2 (0.41) | TGM2PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10088476-B2 | Volume response sensors having analyte controlled reversible crosslinking | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-10-02 | — | — | US | disclosed |
| US-20160252505-A1 | VOLUME RESPONSE SENSORS HAVING ANALYTE CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI S (US) | 2016-09-01 | — | — | US | disclosed |
| WO-2015053975-A1 | VOLUME RESPONSE SENSORS HAVING CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-16 | — | — | WO | disclosed |