Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11192228 | 0.82 | TGM2 (0.48) | TGM2MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL2144451 | 0.79 | TGM2 (0.48) | TGM2MEN1KMT2ACYP1A2ALDH1A1 | |
| SCHEMBL16634557 | 0.79 | TGM2 (0.41) | TGM2 | |
| SCHEMBL15333124 | 0.78 | MAPT (0.44) | MEN1KMT2ACYP1A2ALDH1A1POLB | |
| SCHEMBL29757976 | 0.77 | TGM2 (0.56) | TGM2MEN1KMT2AALDH1A1MAP2K7 | |
| SCHEMBL4903618 | 0.75 | TGM2 (0.61) | TGM2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16634646 | 0.75 | TGM2 (0.45) | TGM2KMT2AALDH1A1TDP1 | |
| SCHEMBL31680492 | 0.75 | TGM2 (0.56) | TGM2MEN1KMT2AALDH1A1MAP2K7 | |
| SCHEMBL1517135 | 0.74 | CYP1A2 (0.45) | CYP1A2ALDH1A1POLBTDP1MAPT | |
| SCHEMBL16634488 | 0.73 | LOXL2 (0.46) | CYP1A2ALDH1A1POLBTDP1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10088476-B2 | Volume response sensors having analyte controlled reversible crosslinking | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2018-10-02 | — | — | US | disclosed |
| US-20160252505-A1 | VOLUME RESPONSE SENSORS HAVING ANALYTE CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOI S (US) | 2016-09-01 | — | — | US | disclosed |
| WO-2015053975-A1 | VOLUME RESPONSE SENSORS HAVING CONTROLLED REVERSIBLE CROSSLINKING | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2015-04-16 | — | — | WO | disclosed |