Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | AKR1C4 | P17516 | 3/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | CASP6 | P55212 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634621 | 1.00 | HCAR3 (0.53) | HCAR3MEN1KMT2APOLBAKR1C4 | |
| SCHEMBL16634858 | 0.84 | HCAR3 (0.63) | HCAR3MEN1KMT2APOLBAKR1C4 | |
| SCHEMBL16634860 | 0.84 | HCAR3 (0.63) | HCAR3MEN1KMT2APOLBAKR1C4 | |
| SCHEMBL3602490 | 0.82 | ATM (0.51) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL16634650 | 0.79 | DHODH (0.57) | HCAR3MEN1KMT2APOLBMAPT | |
| SCHEMBL16634648 | 0.79 | DHODH (0.57) | HCAR3MEN1KMT2APOLBMAPT | |
| SCHEMBL4055608 | 0.79 | MEN1 (0.49) | MEN1KMT2AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL20475343 | 0.76 | KDM4E (0.55) | MEN1KMT2AAKR1C4AKR1C3AKR1C2 | |
| SCHEMBL9537323 | 0.75 | CASP6 (0.51) | HCAR3MEN1KMT2APOLBMAPT | |
| SCHEMBL16634595 | 0.75 | HCAR3 (0.57) | HCAR3MEN1KMT2APOLBAKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |