Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | GFER | P55789 | 4/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | RARB | P10826 | 1/20 | 0.40 |
| ▸ | RARG | P13631 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16634544 | 0.84 | MAPT (0.48) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL16634547 | 0.84 | MAPT (0.48) | GAAMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5095969 | 0.76 | ACACB (0.50) | HSD17B10SMN1; SMN2RAB9ANPC1CYP26A1 | |
| SCHEMBL16634719 | 0.72 | AURKA (0.37) | KDM4EHSD17B10MEN1KMT2AALDH1A1 | |
| SCHEMBL15262867 | 0.71 | PLA2G2A (0.43) | MEN1KMT2ACYP26A1CYP3A4CACNA1H | |
| SCHEMBL6304640 | 0.70 | PARP10 (0.54) | KMT2AALDH1A1ACACB | |
| SCHEMBL16634655 | 0.70 | GAA (0.59) | GAAKDM4EGFERHSD17B10MEN1 | |
| SCHEMBL376772 | 0.68 | BACE1 (0.39) | RAB9ANPC1CACNA1H | |
| SCHEMBL25256213 | 0.67 | FLT3 (0.41) | KDM4EKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL12353208 | 0.67 | TP53 (0.54) | MEN1KMT2ARARBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015052675-A1 | SUBSTITUTED DIHYDRO-BENZIMIDAZOLE COMPOUNDS AS ROR GAMMA MODULATORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2015-04-16 | — | — | WO | disclosed |