Gamolenic Acid

Gamolenic Acid

SCHEMBL16637145

CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O.CCCCC/C=C\C/C=C\C/C=C\CCCCC(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARG P37231 7/20 1.00
PPARD Q03181 6/20 1.00
PPARA Q07869 6/20 1.00
F7 P08709 5/20 1.00
F3 P13726 5/20 1.00
FFAR1 O14842 3/20 1.00
PTGS1 P23219 3/20 1.00
L3MBTL1 Q9Y468 2/20 1.00
ESR1 P03372 1/20 1.00
SRD5A2 P31213 1/20 1.00
CASP6 P55212 1/20 1.00
ALDH1A1 P00352 5/20 0.96
FABP4 P15090 4/20 0.96
HSD17B10 Q99714 4/20 0.96
LMNA P02545 3/20 0.96
CYP19A1 P11511 3/20 0.96
ALOX15 P16050 3/20 0.96
NR4A2 P43354 3/20 0.96
KDM4E B2RXH2 2/20 0.96
CYP3A4 P08684 2/20 0.96

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Gamolenic Acid SCHEMBL6686740 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
Gamolenic Acid SCHEMBL6686744 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
SCHEMBL2852855 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
SCHEMBL2852857 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
Gamolenic Acid SCHEMBL154896 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
SCHEMBL15902383 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
SCHEMBL25316078 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
Gamolenic Acid SCHEMBL604875 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
SCHEMBL15610707 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3
SCHEMBL7552065 1.00 PPARG (1.00) PPARGPPARDPPARAF7F3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9663824-B2 Compositions and methods for epigenetic regulation of long chain polyunsaturated fatty acid production WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2017-05-30 US disclosed
US-20160244840-A1 COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF LONG CHAIN POLYUNSATURATED FATTY ACID PRODUCTION WAKE FOREST UNIVERSITY HEALTH SCIENCES 2016-08-25 US disclosed
CN-104946539-A Mucor circinelloides strain with high grease yield and application thereof UNIV JIANGNAN 2015-09-30 CN disclosed
WO-2015054645-A1 COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF LONG CHAIN POLYUNSATURATED FATTY ACID PRODUCTION WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2015-04-16 WO disclosed
CN-101124330-A Recombinant production of docosahexaenoic acid (DHA) in yeast AVESTHA GENGRAINE TECH PVT LTD (IN) 2008-02-13 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160244840-A1 COMPOSITIONS AND METHODS FOR EPIGENETIC REGULATION OF LONG CHAIN POLYUNSATURATED FATTY ACID PRODUCTION ELOVL3, ELOVL1, ELOVL6 PPARG 183/4885PPARD 808/4885PPARA 481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.