Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 12/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.32 |
| ▸ | FNTB | P49356 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16637829 | 0.92 | SLC6A2 (0.40) | CTSKBTKMEN1USP2ALDH1A1 | |
| SCHEMBL16635863 | 0.82 | CTSK (0.42) | CTSKALOX5APFFAR4BTKALDH1A1 | |
| SCHEMBL16636141 | 0.82 | CTSK (0.42) | CTSKALOX5APFFAR4BTKALDH1A1 | |
| SCHEMBL16635864 | 0.82 | CTSK (0.49) | CTSKALOX5APBTKALDH1A1FNTA | |
| SCHEMBL16636142 | 0.82 | CTSK (0.49) | CTSKALOX5APBTKALDH1A1FNTA | |
| SCHEMBL16636094 | 0.75 | SLC6A2 (0.42) | CTSKBTKUSP2ALDH1A1 | |
| SCHEMBL16636097 | 0.75 | CTSK (0.49) | CTSKALDH1A1 | |
| SCHEMBL16636575 | 0.75 | CTSK (0.49) | CTSKALDH1A1 | |
| SCHEMBL16638075 | 0.72 | CTSK (0.44) | CTSK | |
| SCHEMBL16635762 | 0.71 | FNTA (0.43) | ALOX5APBTKCYP3A4SMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015051479-A1 | CATHEPSIN CYSTEINE PROTEASE INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2015-04-16 | — | — | WO | disclosed |